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Lasers Aim to Replace Scalpels in Cutting-Edge Biopsy Technique

05-16-19

Professor Lihong Wang and Postdoctoral Scholar Dr. Junhui Shi have developed a new imaging technique that uses pulses from two kinds of lasers to take pictures of microscopic biological structures. This new approach, called ultraviolet-localized mid-infrared photoacoustic microscopy, or ULM-PAM, develops images of the microscopic structures found in a piece of tissue by bombarding the sample with both infrared and ultraviolet laser light. "Because ultraviolet light and infrared have different properties, we had to find special mirrors and glass that could focus both," Dr. Shi says. "And because no camera exists that can see both, we had to develop ways to see if they were correctly focused." [Caltech story]

Tags: EE research highlights MedE Lihong Wang postdocs Junhui Shi

President Rosenbaum Highlights Postdocs as "Unsung Heroes"

09-24-18

In a letter to the Caltech community during National Postdoc Appreciation Week, the Caltech President emphasizes the role this key group plays at the Institute. He stated, “Caltech's mission of world-leading research and education depends crucially on our postdoctoral scholars. Although their time at Caltech may be short, they quickly become vital parts of the Institute's intellectual fabric.” [President’s Letter] [EAS Postdoc Resource Page]

Tags: APhMS EE GALCIT MedE MCE CMS ESE Thomas Rosenbaum postdocs

Dragonfly Larvae Inspire New Designs for Prosthetic Heart Valves

07-17-18

Professor Mory Gharib and postdoctoral researcher Chris Roh (MS '13, PhD '17) have studied the design and control of the jets that dragonfly larvae use to propel themselves to re-design health values. "The current heart valve design is a one-size-fits-all, where no patient-specific design is considered, and this causes many post-transplant complications," Dr. Roh says. "We believe that an intentionally off-centered opening of the heart valve to more closely match the patient's original blood flow will be an important design parameter that can be adjusted based on each patient's heart morphology." [Caltech story]

Tags: research highlights GALCIT MedE Morteza Gharib Chris Roh postdocs

Popping Microbubbles Help Focus Light Inside the Body

12-03-15

Changhuei Yang, Professor of Electrical Engineering, Bioengineering, and Medical Engineering, and his postdoctoral colleague Dr. Haowen Ruan have developed a novel technique called time-reversed ultrasound microbubble encoded (TRUME) that uses gas-filled microbubbles to focus light inside tissue. "Ultrasound and X-ray techniques can only detect cancer after it forms a mass," Yang says. "But with optical focusing, you could catch cancerous cells while they are undergoing biochemical changes but before they undergo morphological changes." [Caltech story]

Tags: EE Changhuei Yang MedE health research highlight postdocs

Student Research in Biomedical Optics Wins First Place

07-02-15

Electrical Engineering postdoctoral scholar Dr. Haowen Ruan and graduate student Mooseok Jang, who work with Professor Changhuei Yang, have won first place for Best Student Poster Presentation at the Engineering Conferences International (ECI) series entitled “Advances in Optics in Biotechnology, Medicine and Surgery XIV.” Their winning poster demonstrated research in biomedical optics, specifically a novel technique that focuses light inside biological tissue by time-reversing the light encoded through popping of a microbubble. The technique has the potential to enable one to “see” through biological bodies with light.

Tags: EE honors Changhuei Yang MedE research highlight Haowen Ruan Mooseok Jang postdocs

A New Tool for Secret Agents—And the Rest of Us

12-10-12

Ali Hajimiri, Thomas G. Myers Professor of Electrical Engineering, and Postdoctoral Scholar in Electrical Engineering, Kaushik Sengupta, have developed tiny inexpensive silicon microchips that generate terahertz (THz) waves that fall into a largely untapped region of the electromagnetic spectrum and that can penetrate a host of materials without the ionizing damage of X-rays. When incorporated into handheld devices, the new microchips could enable a broad range of applications in fields ranging from homeland security to wireless communications to health care, and even touchless gaming. "This extraordinary level of creativity, which has enabled imaging in the terahertz frequency range, is very much in line with Caltech's long tradition of innovation in the area of CMOS technology," says Chair Ares Rosakis. "Caltech engineers, like Ali Hajimiri, truly work in an interdisciplinary way to push the boundaries of what is possible." [Caltech Release]

Tags: EE energy research highlights MedE health Ali Hajimiri Kaushik Sengupta postdocs